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Pacijente treba pažljivo pratiti u cilju prepoznavanja znakova i simptoma respiratorne depresije i sedacije. U ovom pogledu se preporučuje informisanje pacijenata i njihovih staratelja (kada je to primenljivo) o značajnosti prepoznavanja ovih simptoma (videti odeljak 4.five).Ukoliko ste trudni ili dojite, mislite da ste trudni ili planirate trud

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